Targeting hyaluronan for the treatment of pancreatic ductal adenocarcinoma

• Главные авторы: Norihiro Sato (Автор), Xiao-Bo Cheng (Автор), Shiro Kohi (Автор), Atsuhiro Koga (Автор), Keiji Hirata (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2016-03-01T00:00:00Z.
• Предметы: article
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Progression of cancer is often associated with interactions between cancer cells and extracellular matrix (ECM) surrounding them. Increasing evidence has suggested that accumulation of hyaluronan (HA), a major component of ECM, provides a favorable microenvironment for cancer progression. Pancreatic...