Transient Receptor Potential Ankyrin 1 (TRPA1) Modulation by 4-Hydroxynonenal (4-HNE) in Pancreatic Adenocarcinoma Cell Lines: Putative Roles for Therapies

• Главные авторы: Florentina Piciu (Автор), Dan Domocos (Автор), Gabriela Chiritoiu (Автор), Marioara Chiritoiu-Butnaru (Автор), Maria Mernea (Автор), Cezar Gabriel Popescu (Автор), Dragos Paul Mihai (Автор), Bianca Galateanu (Автор), Ariana Hudita (Автор), Alexandru Babes (Автор), Dana Cucu (Автор)
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• Опубликовано: MDPI AG, 2024-03-01T00:00:00Z.
• Предметы: article
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Background: Transient receptor potential channels (TRP) are overexpressed in some pancreatic adenocarcinoma (PDAC) patients and cell lines, settling them as putative therapeutic targets in this disease. Reactive oxygen species (ROS), with levels increased in PDAC, modulate some members of the TRP fa...