Bridging population pharmacokinetic and semimechanistic absorption modeling of APX3330
Abstract APX3330 ((2E)‐2‐[(4,5‐dimethoxy‐2‐methyl‐3,6‐dioxo‐1,4‐cyclohexadien‐1‐yl)methylene]‐undecanoic acid), a selective inhibitor of APE1/Ref‐1, has been investigated in treatment of hepatitis, cancer, diabetic retinopathy, and macular edema. APX3330 is administered orally as a quinone but is ra...
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| Main Authors: | , , , , |
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| Format: | Book |
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Wiley,
2024-01-01T00:00:00Z.
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