Co-micronized palmitoylethanolamide/polydatin treatment causes endometriotic lesion regression in a rodent model of surgically-induced endometriosis

• Main Authors: Rosanna Di Paola (Author), Roberta Fusco (Author), Enrico Gugliandolo (Author), Rosalia Crupi (Author), Maurizio Evangelista (Author), Roberta Granese (Author), Salvatore Cuzzocrea (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endometriosis is a chronic, painful disease characterized by the presence of endometrial glands and stroma outside the uterine cavity. Palmitoylethanolamide (PEA), an endogenous fatty acid amide, has anti-inflammatory and neuroprotective effects. PEA lacks free radical scavenging activity, unlike po...