A method to improve quantitative radiotracing‐based analysis of the in vivo biodistribution of drug carriers

• Main Authors: Nikša Roki (Author), Melani Solomon (Author), Lou Casta (Author), Jessica Bowers (Author), Robert C. Getts (Author), Silvia Muro (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Biodistribution studies are essential in drug carrier design and translation, and radiotracing provides a sensitive quantitation for this purpose. Yet, for biodegradable formulations, small amounts of free‐label signal may arise prior to or immediately after injection in animal models, caus...