Neutrophil Cathepsin G, but Not Elastase, Induces Aggregation of MCF-7 Mammary Carcinoma Cells by a Protease Activity-Dependent Cell-Oriented Mechanism

• Príomhchruthaitheoirí: Satoru Yui (Údar), Yuuki Osawa (Údar), Takeo Ichisugi (Údar), Riyo Morimoto-Kamata (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Hindawi Limited, 2014-01-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity. In this study, we examined whether aggregation is caused by degradation of adhesi...