Safety of Mesenchymal Stem Cells for Clinical Application
Mesenchymal stem cells (MSCs) hold great promise as therapeutic agents in regenerative medicine and autoimmune diseases, based on their differentiation abilities and immunosuppressive properties. However, the therapeutic applications raise a series of questions about the safety of culture-expanded M...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Book |
| Published: |
Hindawi Limited,
2012-01-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
MARC
| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_2a85fd1fda2046a9af6c67c4fb482899 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Youwei Wang |e author |
| 700 | 1 | 0 | |a Zhi-bo Han |e author |
| 700 | 1 | 0 | |a Yong-ping Song |e author |
| 700 | 1 | 0 | |a Zhong Chao Han |e author |
| 245 | 0 | 0 | |a Safety of Mesenchymal Stem Cells for Clinical Application |
| 260 | |b Hindawi Limited, |c 2012-01-01T00:00:00Z. | ||
| 500 | |a 1687-966X | ||
| 500 | |a 1687-9678 | ||
| 500 | |a 10.1155/2012/652034 | ||
| 520 | |a Mesenchymal stem cells (MSCs) hold great promise as therapeutic agents in regenerative medicine and autoimmune diseases, based on their differentiation abilities and immunosuppressive properties. However, the therapeutic applications raise a series of questions about the safety of culture-expanded MSCs for human use. This paper summarized recent findings about safety issues of MSCs, in particular their genetic stability in long-term in vitro expansion, their cryopreservation, banking, and the role of serum in the preparation of MSCs. | ||
| 546 | |a EN | ||
| 690 | |a Internal medicine | ||
| 690 | |a RC31-1245 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Stem Cells International, Vol 2012 (2012) | |
| 787 | 0 | |n http://dx.doi.org/10.1155/2012/652034 | |
| 787 | 0 | |n https://doaj.org/toc/1687-966X | |
| 787 | 0 | |n https://doaj.org/toc/1687-9678 | |
| 856 | 4 | 1 | |u https://doaj.org/article/2a85fd1fda2046a9af6c67c4fb482899 |z Connect to this object online. |