Low-Dose Acetylsalicylic Acid and Mitochondria-Targeted Antioxidant Mitoquinone Attenuate Non-Alcoholic Steatohepatitis in Mice

• Main Authors: Saadet Turkseven (Author), Cristian Turato (Author), Gianmarco Villano (Author), Mariagrazia Ruvoletto (Author), Maria Guido (Author), Massimo Bolognesi (Author), Patrizia Pontisso (Author), Marco Di Pascoli (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. NAFLD can evolve from simple fatty liver to non-alcoholic steatohepatitis (NASH), and ultimately, to cirrhosis. Inflammation and oxidative stress, promoted by mitochondrial dysfunction, play a crucial role in the ons...