Parathyroid hormone in renal transplanted recipients; a single center study

• Main Authors: Nasri Hamid (Author), Rafieian-Kopaei Mahmoud (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2345-4202
• Keywords: Parathormone; Transplantation; Parathyroid gland; Therapeutics. Pharmacology; RM1-950; Diseases of the genitourinary system. Urology; RC870-923
• Source: Journal of Nephropharmacology, Vol 2, Iss 1, Pp 3-4 (2013)

This investigation, aimed to study of intact parathormone (iPTH) and calcium (Ca) in a group of kidney transplanted patients and also we aimed to test the relationship of iPTH with various demographic data of kidney transplanted recipients. We studied 72 kidney transplanted persons with mean ages of 44±12 years. In this study, mean iPTH was 18.4±8.2 Pg/mL (median=16.5). A negative correlation of iPTH with creatinine clearance (r=-0.44, p<0.001) was seen. There was no any association between the time of kidney transplantation and serum iPTH (p>0.05). In contrast to previous findings, in our patients, there was not secondary hyperparathyroidism. The results revealed suppressed PTH secretion. The reason may be due to excessive intake of calcium and Vitamin D analogues, which may suppress parathyroid hormone secretion.