Poorly differentiated monophasic synovial sarcoma of the mediastinum

Poorly differentiated synovial sarcoma is a diagnostically challenging neoplasm. Most commonly they occur in the soft tissue of the extremities and are rare in the mediastinum. They can be indistinguishable from other "round cell tumors" based on the morphology alone or at times by immunoh...

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Bibliographic Details
Main Authors: Maha Arafah (Author), Shaesta N Zaidi (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
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100 1 0 |a Maha Arafah  |e author 
700 1 0 |a Shaesta N Zaidi  |e author 
245 0 0 |a Poorly differentiated monophasic synovial sarcoma of the mediastinum 
260 |b Wolters Kluwer Medknow Publications,   |c 2011-01-01T00:00:00Z. 
500 |a 0377-4929 
500 |a 10.4103/0377-4929.81650 
520 |a Poorly differentiated synovial sarcoma is a diagnostically challenging neoplasm. Most commonly they occur in the soft tissue of the extremities and are rare in the mediastinum. They can be indistinguishable from other "round cell tumors" based on the morphology alone or at times by immunohistochemical studies. Here in, we report an extremely rare case of metastatic poorly differentiated monophasic synovial sarcoma of the mediastinum without a known primary in a 30-year-old man. The imaging studies on admission showed 10 × 9.5 cm anterior mediastinal mass with multiple nodules in the lung and pleura along with multiple enlarged mediastinal and axillary lymph nodes. Histopathologic and immunohistochemical analysis supported the diagnosis of poorly differentiated synovial sarcoma, which was further confirmed by molecular genetic analysis. 
546 |a EN 
690 |a Immunohistochemistry 
690 |a mediastinum 
690 |a synovial sarcoma 
690 |a Pathology 
690 |a RB1-214 
690 |a Microbiology 
690 |a QR1-502 
655 7 |a article  |2 local 
786 0 |n Indian Journal of Pathology and Microbiology, Vol 54, Iss 2, Pp 384-387 (2011) 
787 0 |n http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2011;volume=54;issue=2;spage=384;epage=387;aulast=Arafah 
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