Staphylococcal Scalded Skin Syndrome in Neonates: Case Series and Overview of Outbreaks
Skin and soft tissue infections caused by <i>Staphylococcus aureus</i> (<i>S. aureus</i>) cover a wide spectrum of diseases in neonates, including staphylococcal scalded skin syndrome (SSSS). We describe a representative case of SSSS in neonatal twins, which despite recurrenc...
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| Main Authors: | , , , |
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| Format: | Book |
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MDPI AG,
2022-12-01T00:00:00Z.
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| Summary: | Skin and soft tissue infections caused by <i>Staphylococcus aureus</i> (<i>S. aureus</i>) cover a wide spectrum of diseases in neonates, including staphylococcal scalded skin syndrome (SSSS). We describe a representative case of SSSS in neonatal twins, which despite recurrence showed a mild clinical disease course. This case was part of a small outbreak on a neonatal intensive care unit and therefore exemplifies the existence of neonatal outbreaks with skin and soft tissue infections by <i>S. aureus.</i> Diagnosis is generally based on the clinical picture and response to antibiotics, but can be aided by histology and cultures. Sequence-based molecular techniques are available to evaluate typing and virulence of S. <i>aureus</i> in outbreak or surveillance settings. The pillars of treatment are antibiotics and supportive care. Methicillin resistance remains a topic of concern, especially in outbreak settings. Our overview of numerous outbreaks of neonatal S. <i>aureus</i> skin infections underlines the importance of outbreak management strategies, including screening to identify the source of the outbreak, and limiting exposure through hygienic measures and establishment of physical boundaries. |
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| Item Description: | 10.3390/antibiotics12010038 2079-6382 |