Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity

• Main Authors: Felicia D'Andrea (Author), Stefania Sartini (Author), Ilaria Piano (Author), Matteo Franceschi (Author), Luca Quattrini (Author), Lorenzo Guazzelli (Author), Lidia Ciccone (Author), Elisabetta Orlandini (Author), Claudia Gargini (Author), Concettina La Motta (Author), Susanna Nencetti (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aldose reductase is a key enzyme in the development of long term diabetic complications and its inhibition represents a viable therapeutic solution for people affected by these pathologies. Therefore, the search for effective aldose reductase inhibitors is a timely and pressing challenge. Herein we...