A case of perivascular epithelioid nodules arising in an intramural leiomyoma

Perivascular epithelioid cell (PEC) tumors (PEComas) are a family of related mesenchymal tumors composed of PECs that co-express melanocytic and smooth muscle markers. Their diagnosis is challenging in the female genital organs owing to its morphologic and immunohistochemical overlap with smooth mus...

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Main Authors: Yoldez Houcine (Author), Karima Mekni (Author), Emna Brahem (Author), Mouna Mlika (Author), Aida Ayadi (Author), Chiraz Fekih (Author), Imene Ridene (Author), Faouzi El Mezni (Author)
Format: Book
Published: Elsevier, 2021-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Yoldez Houcine  |e author 
700 1 0 |a Karima Mekni  |e author 
700 1 0 |a Emna Brahem  |e author 
700 1 0 |a Mouna Mlika  |e author 
700 1 0 |a Aida Ayadi  |e author 
700 1 0 |a Chiraz Fekih  |e author 
700 1 0 |a Imene Ridene  |e author 
700 1 0 |a Faouzi El Mezni  |e author 
245 0 0 |a A case of perivascular epithelioid nodules arising in an intramural leiomyoma 
260 |b Elsevier,   |c 2021-03-01T00:00:00Z. 
500 |a 2214-3300 
500 |a 10.1016/j.ehpc.2020.200470 
520 |a Perivascular epithelioid cell (PEC) tumors (PEComas) are a family of related mesenchymal tumors composed of PECs that co-express melanocytic and smooth muscle markers. Their diagnosis is challenging in the female genital organs owing to its morphologic and immunohistochemical overlap with smooth muscle tumors and other clear cell tumors. We report the clinicopathologic and immunohistochemical characteristics. We also discuss differential diagnoses of an unusual tumor of the uterus composed of nodules of epithelioid cells strongly positive for HMB45, arising in a surrounding leiomyoma. We viewed these neoplasms as PEComa. The follow up has shown that the patient was alive without disease 1 year after the surgery. 
546 |a EN 
690 |a Immunohistochemistry 
690 |a Perivascular epithelioid cell neoplasms 
690 |a Uterus 
690 |a Differential diagnosis 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Human Pathology: Case Reports, Vol 23, Iss , Pp 200470- (2021) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S221433002030119X 
787 0 |n https://doaj.org/toc/2214-3300 
856 4 1 |u https://doaj.org/article/2bc337ad594a4affaa1ce9d5d6fe285c  |z Connect to this object online.