Advances in mRNA 5-methylcytosine modifications: Detection, effectors, biological functions, and clinical relevance

• Main Authors: Gangqiang Guo (Author), Kan Pan (Author), Su Fang (Author), Lele Ye (Author), Xinya Tong (Author), Zhibin Wang (Author), Xiangyang Xue (Author), Huidi Zhang (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

5-methylcytosine (m5C) post-transcriptional modifications affect the maturation, stability, and translation of the mRNA molecule. These modifications play an important role in many physiological and pathological processes, including stress response, tumorigenesis, tumor cell migration, embryogenesis...