NADPH Oxidase Isoforms and Anti-hypertensive Effects of Atorvastatin Demonstrated in Two Animal Models

• Main Authors: Wenhao Cui (Author), Kuniharu Matsuno (Author), Kazumi Iwata (Author), Masakazu Ibi (Author), Masato Katsuyama (Author), Tomoko Kakehi (Author), Mika Sasaki (Author), Kanako Ikami (Author), Kai Zhu (Author), Chihiro Yabe-Nishimura (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Beneficial effects of statins on cardiovascular diseases have been attributed to decreased generation of reactive oxygen species (ROS). We tested the hypothesis that atorvastatin protects against the development of hypertension by reducing levels of NADPH oxidase-derived ROS in two hypertensive anim...