Association of three missense mutations in the homocysteine-related MTHFR and MTRR gene with risk of polycystic ovary syndrome in Southern Chinese women

• Main Authors: Wanqin Feng (Author), Yan Zhang (Author), Yuan Pan (Author), Yi Zhang (Author), Minjuan Liu (Author), Yuxin Huang (Author), Yuanling Xiao (Author), Wenyu Mo (Author), Junjie Jiao (Author), Xiaoyang Wang (Author), Dan Tian (Author), Lixia Yang (Author), Ying Ma (Author)
• Format: Book
• Published: BMC, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The etiology between homocysteine and polycystic ovary syndrome (PCOS) is unclear. In humans, the level of homocysteine is mainly affected by two enzymes: methylene tetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR). While the activity of these two enzyme...