Validation of a novel causality assessment scale for adverse events in non-small cell lung carcinoma patients treated with platinum and pemetrexed doublet chemotherapy

• Main Authors: Jyoti Bhagatram Sharma (Author), Manjunath Nookala Krishnamurthy (Author), Ankita Awase (Author), Amit Joshi (Author), Vijay Patil (Author), Vanita Noronha (Author), Kumar Prabhash (Author), Vikram Gota (Author)
• Format: Book
• Published: SAGE Publishing, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Accurate causality assessment (CA) of adverse events (AEs) is important in clinical research and routine clinical practice. The Naranjo scale (NS) used for CA lacks specificity, leading to a high rate of false positive causal associations. NS is a simple scale for CA; however, its limitations h...