Distinct regulatory functions and biological roles of lncRNA splice variants

• Hauptverfasser: Muhammad Riaz Khan (Verfasst von), Mariano Avino (Verfasst von), Raymund J. Wellinger (Verfasst von), Benoit Laurent (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2023-06-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In humans, 90%-95% of multi-exon genes produce alternatively spliced RNA transcripts. Therefore, every single gene has the opportunity of producing multiple splice variants, including long non-coding RNA (lnc...