Distinct regulatory functions and biological roles of lncRNA splice variants

• Autori principali: Muhammad Riaz Khan (Autore), Mariano Avino (Autore), Raymund J. Wellinger (Autore), Benoit Laurent (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2023-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Alternative splicing (AS) of RNA molecules is a key contributor to transcriptome diversity. In humans, 90%-95% of multi-exon genes produce alternatively spliced RNA transcripts. Therefore, every single gene has the opportunity of producing multiple splice variants, including long non-coding RNA (lnc...