Drug Hypersensitivity due to Azathioprine with Elevated Procalcitonin

We present a case of azathioprine hypersensitivity presenting as sepsis with elevated procalcitonin in a 68-year-old man with myasthenia gravis. The patient presented with fever, chills, nausea, vomiting, and headache. He developed numerous 1 cm erythematous papules over his upper torso. Infectious...

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Bibliographic Details
Main Authors: Tania Ahuja (Author), Frank R. Chung (Author), Tania Ruiz-Maya (Author)
Format: Book
Published: Hindawi Limited, 2018-01-01T00:00:00Z.
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Summary:We present a case of azathioprine hypersensitivity presenting as sepsis with elevated procalcitonin in a 68-year-old man with myasthenia gravis. The patient presented with fever, chills, nausea, vomiting, and headache. He developed numerous 1 cm erythematous papules over his upper torso. Infectious workup including bacteriological tests and microbial cultures was negative and a skin biopsy was performed which revealed suppurative folliculitis with eosinophils, consistent with drug hypersensitivity. Notably, acute phase reactants including C-reactive protein and procalcitonin were elevated upon presentation, likely secondary to drug hypersensitivity.
Item Description:2090-6463
2090-6471
10.1155/2018/2648325