Identification of a Novel Alternatively Spliced Form of Inflammatory Regulator SWAP-70-Like Adapter of T Cells

• Main Authors: Marie Hashimoto (Author), Jun-ichi Nagao (Author), Shojiro Ikezaki (Author), Sonoko Tasaki (Author), Ken-ichi (Author), Yuka Narita (Author), Tamaki Cho (Author), Kenji Yuasa (Author), Amnon Altman (Author), Yoshihiko Tanaka (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activation of naive CD4+ T cells results in the development of several distinct subsets of effector Th cells, including Th2 cells that play a pivotal role in allergic inflammation and helminthic infections. SWAP-70-like adapter of T cells (SLAT), also known as Def6 or IBP, is a guanine nucleotide ex...