IL-1Ra Protects Hepatocytes from CCl4-Induced Hepatocellular Apoptosis via Activating the ERK1/2 Pathway

• Main Authors: Ying Zheng (Author), Xinyi Xiao (Author), Zhuoyi Yang (Author), Meiqi Zhou (Author), Hui Chen (Author), Siyi Bai (Author), Jianwei Zhu (Author), Yunsheng Yuan (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin-1 receptor antagonist is an important acute-phase protein and an immune mediator, and its expression is associated with the development of hepatitis or acute liver failure. The aim of this study was to investigate whether recombinant human interleukin-1 receptor antagonist directly targe...