Neutrophilic dermatosis of the dorsal hands: response to dapsone monotherapy

Abstract: Neutrophilic dermatosis of the dorsal hands is considered a rare and localized variant of Sweet's syndrome. Although the etiology is unknown, there are reports of association with infections, neoplasias, autoimmune diseases and medications. Histopathology shows a dense neutrophilic in...

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Bibliographic Details
Main Authors: Felipe Siqueira Ramos (Author), Flávia Regina Ferreira (Author), Fátima Maria de Oliveira Rabay (Author), Marcia Lanzoni de Alvarenga Lira (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia, 2018-10-01T00:00:00Z.
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Summary:Abstract: Neutrophilic dermatosis of the dorsal hands is considered a rare and localized variant of Sweet's syndrome. Although the etiology is unknown, there are reports of association with infections, neoplasias, autoimmune diseases and medications. Histopathology shows a dense neutrophilic inflammatory infiltrate in the dermis. Treatment is based on the administration of systemic corticosteroids; however, a combination of medications is useful, given the frequency of relapses. The authors report a classic and clinically exuberant case of neutrophilic dermatosis of the dorsal hands, with excellent response to oral dapsone treatment, and offer a brief literature review.
Item Description:0365-0596
10.1590/abd1806-4841.20187488