Synthesis of novel 5-substituted 2-pyrazolylthiazol-4-ones as potential bioligically active compounds

• Main Authors: I. M. Yushyn (Author), A. V. Lozynskyi (Author), O.-M. V. Fedusevych (Author), O. Yа. Vovchuk (Author), R. B. Lesyk (Author)
• Format: Book
• Published: Zaporozhye State Medical University, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the effective strategies in potential "drug-like" molecules design is using a molecular hybridization approach based on the combination of several pharmacological scaffolds in one molecule. The main argument for using this approach is a polypharmacological theory based on the intera...