Successful treatment of multifocal cutaneous leishmaniasis with miltefosine

We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurat...

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Main Authors: Bhushan Madke (Author), Vidya Kharkar (Author), Siddhi Chikhalkar (Author), Sunanda Mahajan (Author), Uday Khopkar (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
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100 1 0 |a Bhushan Madke  |e author 
700 1 0 |a Vidya Kharkar  |e author 
700 1 0 |a Siddhi Chikhalkar  |e author 
700 1 0 |a Sunanda Mahajan  |e author 
700 1 0 |a Uday Khopkar  |e author 
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520 |a We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy. 
546 |a EN 
690 |a Leishmaniasis 
690 |a miltefosine 
690 |a multifocal 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Indian Journal of Dermatology, Vol 56, Iss 5, Pp 587-590 (2011) 
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