PH OF THE TOPICAL DRUG VEHICLE: SELECTING AN OPTIMUM VALUE AND ROLE OF THE BUFFER SYSTEM

The following three groups of factors must be taken into consideration for selecting an optimum pH value of a topical drug: pharmaceutical, pharmacological and compatibility factors. To ensure a stable pH value, the drug vehicle comprises different buffer systems: single component and two-component...

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Bibliographic Details
Main Author: A. S. Dukhanin (Author)
Format: Book
Published: State Scientific Center of Dermatovenereology and Cosmetology, 2017-08-01T00:00:00Z.
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Summary:The following three groups of factors must be taken into consideration for selecting an optimum pH value of a topical drug: pharmaceutical, pharmacological and compatibility factors. To ensure a stable pH value, the drug vehicle comprises different buffer systems: single component and two-component ones. The optimum conditions for selecting and maintaining the vehicle pH were examined by the example of glucocorticosteroid-based topical drugs.
Item Description:0042-4609
2313-6294
10.25208/0042-4609-2016-0-2-110-114