tRNA-derived fragments tRFGlnCTG induced by arterial injury promote vascular smooth muscle cell proliferation

• Main Authors: Xiao-Ling Zhu (Author), Tao Li (Author), Yu Cao (Author), Qing-Ping Yao (Author), Xing Liu (Author), Ying Li (Author), Yang-Yang Guan (Author), Ji-Jun Deng (Author), Rui Jiang (Author), Jun Jiang (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

tRNA-derived fragments (tRFs) and tRNA halves (tiRNAs) are originated from the specific cleavage of endogenous tRNAs or their precursors and regulate gene expression when the cells are in stressful circumstances. Here, we replicated the rat common carotid artery (CCA) intimal hyperplasia model and i...