Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters

• Váldodahkki: GEORGE eDIALLINAS (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2014-09-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Transporters are ubiquitous proteins mediating the translocation of solutes across cell membranes, a biological process involved in nutrition, signaling, neurotransmission, cell communication and drug uptake or efflux. Similarly to enzymes, most transporters have a single substrate binding-site and...