Targeted Expression of miR-7 Operated by TTF-1 Promoter Inhibited the Growth of Human Lung Cancer through the NDUFA4 Pathway

• Main Authors: Liangyu Lei (Author), Chao Chen (Author), Juanjuan Zhao (Author), HaiRong Wang (Author), Mengmeng Guo (Author), Ya Zhou (Author), Junming Luo (Author), Jidong Zhang (Author), Lin Xu (Author)
• Format: Book
• Published: Elsevier, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeted expression of gene technique is an important therapeutic strategy for lung cancer. MicroRNA-7 has been well documented as a promising tumor suppressor but never been test in specific gene-promoter-targeted expression in cancer gene therapy. Here, we first evaluated the efficacy of miR-7 exp...