Piperazine- and Piperidine-Containing Thiazolo[5,4-<i>d</i>]pyrimidine Derivatives as New Potent and Selective Adenosine A_2A Receptor Inverse Agonists

• Main Authors: Flavia Varano (Author), Daniela Catarzi (Author), Erica Vigiani (Author), Fabrizio Vincenzi (Author), Silvia Pasquini (Author), Katia Varani (Author), Vittoria Colotta (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The therapeutic use of A_2A adenosine receptor (AR) antagonists for the treatment of neurodegenerative disorders, such as Parkinson and Alzheimer diseases, is a very promising approach. Moreover, the potential therapeutic role of A_2A AR antagonists to avo...