Berberine ameliorates septic cardiomyopathy through protecting mitochondria and upregulating Notch1 signaling in cardiomyocytes

• Main Authors: Qi Shen (Author), Yufan Yuan (Author), Zelin Li (Author), Ying Ling (Author), Jian Wang (Author), Mingjing Gao (Author), Peng Wang (Author), Mengli Li (Author), Lizhong Lai (Author), Jinlan Jin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionSeptic cardiomyopathy (SCM) arises as a consequence of sepsis-associated cardiovascular dysfunction, for which there is currently no specific targeted therapy available. Previous studies have demonstrated the beneficial therapeutic effect of berberine (BBR) on SCM; however, the underlyin...