Enterovirus-Human Rhinovirus: A Rare Cause of Acute Respiratory Distress Syndrome

A 22-year-old Asian woman presented with respiratory distress, cough, and wheezing for 1 week. Prior history included asthma and Turner syndrome. On presentation to the emergency department, the patient was hypotensive, tachycardic, tachypneic, with an oxyhemoglobin saturation in the mid 80% range w...

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Main Authors: Parita Soni MD (Author), Anand Rai MD (Author), Nidhi Aggarwal MD (Author), Stephan Kamholz MD (Author), Taek Yoon MD (Author), Yizhak Kupfer MD (Author)
Format: Book
Published: SAGE Publishing, 2017-09-01T00:00:00Z.
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100 1 0 |a Parita Soni MD  |e author 
700 1 0 |a Anand Rai MD  |e author 
700 1 0 |a Nidhi Aggarwal MD  |e author 
700 1 0 |a Stephan Kamholz MD  |e author 
700 1 0 |a Taek Yoon MD  |e author 
700 1 0 |a Yizhak Kupfer MD  |e author 
245 0 0 |a Enterovirus-Human Rhinovirus: A Rare Cause of Acute Respiratory Distress Syndrome 
260 |b SAGE Publishing,   |c 2017-09-01T00:00:00Z. 
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500 |a 10.1177/2324709617728526 
520 |a A 22-year-old Asian woman presented with respiratory distress, cough, and wheezing for 1 week. Prior history included asthma and Turner syndrome. On presentation to the emergency department, the patient was hypotensive, tachycardic, tachypneic, with an oxyhemoglobin saturation in the mid 80% range while breathing ambient air. Chest radiograph revealed pulmonary vascular congestion and a left lower lobe infiltrate. Endotracheal intubation, mechanical ventilation, and vasopressors were initiated. Empiric therapy for community-acquired pneumonia was administered utilizing broad-spectrum intravenous antibiotics. Routine sputum culture was negative for pathogens. Nasopharyngeal swab submitted for multiplex amplified nucleic acid testing yielded enterovirus-human rhinovirus (EV-HRV). Thus, the diagnosis of EV-HRV pneumonia complicated by acute respiratory distress syndrome (ARDS) was established. Multiple attempts to wean from the ventilator were unsuccessful, and a tracheostomy was performed. This report highlights EV-HRV as a cause of severe ARDS and prolonged respiratory failure in adults. 
546 |a EN 
690 |a Medicine (General) 
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690 |a Pathology 
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655 7 |a article  |2 local 
786 0 |n Journal of Investigative Medicine High Impact Case Reports, Vol 5 (2017) 
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787 0 |n https://doaj.org/toc/2324-7096 
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