Feeding Modalities and the Onset of the Neonatal Abstinence Syndrome

AbstractBreast milk has been reported to ameliorate the severity and outcome of neonatal abstinence syndrome (NAS). The mechanism of this beneficial effect of breast milk on NAS remains unclear, as the negligible amount of methadone transmitted via breast milk is unlikely to have an impact on NAS. T...

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Główni autorzy: Anthony eLiu (Autor), Jamie eJuarez (Autor), Ajitha eNair (Autor), Ralph Kay Heinrich Nanan (Autor)
Format: Książka
Wydane: Frontiers Media S.A., 2015-02-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Anthony eLiu  |e author 
700 1 0 |a Jamie eJuarez  |e author 
700 1 0 |a Ajitha eNair  |e author 
700 1 0 |a Ralph Kay Heinrich Nanan  |e author 
245 0 0 |a Feeding Modalities and the Onset of the Neonatal Abstinence Syndrome 
260 |b Frontiers Media S.A.,   |c 2015-02-01T00:00:00Z. 
500 |a 2296-2360 
500 |a 10.3389/fped.2015.00014 
520 |a AbstractBreast milk has been reported to ameliorate the severity and outcome of neonatal abstinence syndrome (NAS). The mechanism of this beneficial effect of breast milk on NAS remains unclear, as the negligible amount of methadone transmitted via breast milk is unlikely to have an impact on NAS. The aim of this study was to compare the impact of different feeding modalities on the onset of NAS.A retrospective medical record review was conducted on one hundred and ninety-four methadone maintained mother/infant dyads. Infants were categorized on the first 2 days of life as predominantly breastfed, fed expressed human breast milk or formula fed. The feeding categories were then analyzed using the onset of NAS as the outcome measure. After adjusting for confounders, there was no significant effect of the modality of feeding on the rates of NAS requiring treatment (p=0.11). Breastfeeding significantly delayed the onset of NAS (p=0.04)The act of breastfeeding in the first two days of life had no effect on whether an infant required treatment for NAS when compared to those fed EBM or formula. This only suggests that the advantages of breastfeeding on NAS cannot be substantiated in a small cohort and should not discourage breastfeeding. 
546 |a EN 
690 |a Methadone 
690 |a Neonatal Abstinence Syndrome 
690 |a breastfeeding 
690 |a breast milk 
690 |a feeding modalities 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Frontiers in Pediatrics, Vol 3 (2015) 
787 0 |n http://journal.frontiersin.org/Journal/10.3389/fped.2015.00014/full 
787 0 |n https://doaj.org/toc/2296-2360 
856 4 1 |u https://doaj.org/article/2dd4e65b22a14e1ab5f7cf0c5caa72a4  |z Connect to this object online.