Association of Beta-Thalassaemia and Hypogonadotropic Hypogonadism

Thalassaemic syndromes are among the most common haemoglobinopathies and are associated with high morbidity and mortality. Because of the various treatments, a secondary endocrinopathy due to iron overload-haemosiderosis-can occur, causing hypopituitarism leading to hypogonadotropic hypogonadism (HH...

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Main Authors: Angela Vidal (Author), Carolin Dhakal (Author)
Format: Book
Published: Hindawi Limited, 2022-01-01T00:00:00Z.
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100 1 0 |a Angela Vidal  |e author 
700 1 0 |a Carolin Dhakal  |e author 
245 0 0 |a Association of Beta-Thalassaemia and Hypogonadotropic Hypogonadism 
260 |b Hindawi Limited,   |c 2022-01-01T00:00:00Z. 
500 |a 2090-6692 
500 |a 10.1155/2022/4655249 
520 |a Thalassaemic syndromes are among the most common haemoglobinopathies and are associated with high morbidity and mortality. Because of the various treatments, a secondary endocrinopathy due to iron overload-haemosiderosis-can occur, causing hypopituitarism leading to hypogonadotropic hypogonadism (HH) and infertility. We present a case of secondary amenorrhoea in a patient with beta-thalassaemia and a history of multiple therapies in her adolescence, such as multiple transfusions, chemotherapy, and allogeneic bone marrow transplantation, who presented with HH and premature ovarian insufficiency. 
546 |a EN 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Case Reports in Obstetrics and Gynecology, Vol 2022 (2022) 
787 0 |n http://dx.doi.org/10.1155/2022/4655249 
787 0 |n https://doaj.org/toc/2090-6692 
856 4 1 |u https://doaj.org/article/2e35dcd33bf34c00b30f300c3b58e8fb  |z Connect to this object online.