Case report of cutaneous histiocytic sarcoma: diagnostic and therapeutic dilemmas

Histiocytic sarcoma is a rare hematologic malignant neoplasia originating from histiocytic or dendritic cell clones. The lesions may be in nodal or extranodal sites, most commonly in the gastrointestinal tract. A small number of cases presents as unique cutaneous lesions. The definitive diagnosis is...

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Main Authors: Flavia Trevisan (Author), Celia Antonia Xavier (Author), Clovis Antonio Lopes Pinto (Author), Fernanda Gomes Cattete (Author), Fabiola Schauffler Stock (Author), Marcella Ledo Martins (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia, 2013-10-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Flavia Trevisan  |e author 
700 1 0 |a Celia Antonia Xavier  |e author 
700 1 0 |a Clovis Antonio Lopes Pinto  |e author 
700 1 0 |a Fernanda Gomes Cattete  |e author 
700 1 0 |a Fabiola Schauffler Stock  |e author 
700 1 0 |a Marcella Ledo Martins  |e author 
245 0 0 |a Case report of cutaneous histiocytic sarcoma: diagnostic and therapeutic dilemmas 
260 |b Sociedade Brasileira de Dermatologia,   |c 2013-10-01T00:00:00Z. 
500 |a 0365-0596 
500 |a 10.1590/abd1806-4841.20132070 
520 |a Histiocytic sarcoma is a rare hematologic malignant neoplasia originating from histiocytic or dendritic cell clones. The lesions may be in nodal or extranodal sites, most commonly in the gastrointestinal tract. A small number of cases presents as unique cutaneous lesions. The definitive diagnosis is made by positivity for the immunohistochemical markers CD163, CD68, CD4 and lysozyme. The treatment is controversial, often with combined systemic chemotherapy. This is a case of cutaneous histiocytic sarcoma in an 82-year-old patient presenting two nodular lesions in the breast and right arm which were treated with simple excision and multidisciplinary follow-up, avoiding aggressive management and exhaustive investigations. Although most studies report aggressive evolution, the patient had good and stable clinical status during the twelve-month follow-up period. 
546 |a EN 
546 |a PT 
690 |a Histiocytic disorders, malignant 
690 |a Histiocytic sarcoma 
690 |a Immunohistochemistry 
690 |a Sarcoma 
690 |a Therapeutics 
690 |a Treatment outcome 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Anais Brasileiros de Dermatologia, Vol 88, Iss 5, Pp 807-810 (2013) 
787 0 |n http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962013000500807&tlng=en 
787 0 |n http://www.scielo.br/pdf/abd/v88n5/0365-0596-abd-88-05-0807.pdf 
787 0 |n https://doaj.org/toc/0365-0596 
856 4 1 |u https://doaj.org/article/2e4f1fd76a774af499c9cd29c94e19d0  |z Connect to this object online.