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Therapy of Organophosphate Poisoning via Intranasal Administration of 2-PAM-Loaded Chitosomes

Chitosan-decorated liposomes were proposed for the first time for the intranasal delivery of acetylcholinesterase (AChE) reactivator pralidoxime chloride (2-PAM) to the brain as a therapy for organophosphorus compounds (OPs) poisoning. Firstly, the chitosome composition based on phospholipids, chole...

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Main Authors: Elmira A. Vasilieva (Author), Darya A. Kuznetsova (Author), Farida G. Valeeva (Author), Denis M. Kuznetsov (Author), Andrey V. Zakharov (Author), Syumbelya K. Amerhanova (Author), Alexandra D. Voloshina (Author), Irina V. Zueva (Author), Konstantin A. Petrov (Author), Lucia Ya. Zakharova (Author)
Format: Book
Published: MDPI AG, 2022-12-01T00:00:00Z.
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