Induced pluripotent stem cells representing Nakajo-Nishimura syndrome

• Автори: Nobuo Kanazawa (Автор), Fumiko Honda-Ozaki (Автор), Megumu K. Saito (Автор)
• Формат: Книга
• Опубліковано: BMC, 2019-05-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Nakajo-Nishimura syndrome is a proteasome-associated autoinflammatory syndrome with a distinct homozygous mutation in the PSMB8 gene encoding an inducible β5i subunit of the immunoproteasome. Although it is considered that immunoproteasome dysfunction causes cellular stress and contributes...