SARS-CoV-2 infection during pregnancy and pregnancy-related conditions: Concerns, challenges, management and mitigation strategies-a narrative review

The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health problem. The SARS-CoV-2 triggers hyper-activation of inflammatory and immune responses resulting in cytokine storm and increased inflammatory re...

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Main Authors: Rakesh Kumar (Author), Cut Meurah Yeni (Author), Niken Asri Utami (Author), Rupali Masand (Author), Rajesh Kumar Asrani (Author), Shailesh Kumar Patel (Author), Akshay Kumar (Author), Mohd. Iqbal Yatoo (Author), Ruchi Tiwari (Author), Senthilkumar Natesan (Author), Kranti Suresh Vora (Author), Firzan Nainu (Author), Muhammad Bilal (Author), Manish Dhawan (Author), Talha Bin Emran (Author), Tauseef Ahmad (Author), Harapan Harapan (Author), Kuldeep Dhama (Author)
Format: Book
Published: Elsevier, 2021-07-01T00:00:00Z.
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100 1 0 |a Rakesh Kumar  |e author 
700 1 0 |a Cut Meurah Yeni  |e author 
700 1 0 |a Niken Asri Utami  |e author 
700 1 0 |a Rupali Masand  |e author 
700 1 0 |a Rajesh Kumar Asrani  |e author 
700 1 0 |a Shailesh Kumar Patel  |e author 
700 1 0 |a Akshay Kumar  |e author 
700 1 0 |a Mohd. Iqbal Yatoo  |e author 
700 1 0 |a Ruchi Tiwari  |e author 
700 1 0 |a Senthilkumar Natesan  |e author 
700 1 0 |a Kranti Suresh Vora  |e author 
700 1 0 |a Firzan Nainu  |e author 
700 1 0 |a Muhammad Bilal  |e author 
700 1 0 |a Manish Dhawan  |e author 
700 1 0 |a Talha Bin Emran  |e author 
700 1 0 |a Tauseef Ahmad  |e author 
700 1 0 |a Harapan Harapan  |e author 
700 1 0 |a Kuldeep Dhama  |e author 
245 0 0 |a SARS-CoV-2 infection during pregnancy and pregnancy-related conditions: Concerns, challenges, management and mitigation strategies-a narrative review 
260 |b Elsevier,   |c 2021-07-01T00:00:00Z. 
500 |a 1876-0341 
500 |a 10.1016/j.jiph.2021.04.005 
520 |a The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health problem. The SARS-CoV-2 triggers hyper-activation of inflammatory and immune responses resulting in cytokine storm and increased inflammatory responses on several organs like lungs, kidneys, intestine, and placenta. Although SARS-CoV-2 affects individuals of all age groups and physiological statuses, immune-compromised individuals such as pregnant women are considered as a highly vulnerable group. This review aims to raise the concerns of high risk of infection, morbidity and mortality of COVID-19 in pregnant women and provides critical reviews of pathophysiology and pathobiology of how SARS-CoV-2 infection potentially increases the severity and fatality during pregnancy. This article also provides a discussion of current evidence on vertical transmission of SARS-CoV-2 during pregnancy and breastfeeding. Lastly, guidelines on management, treatment, preventive, and mitigation strategies of SARS-CoV-2 infection during pregnancy and pregnancy-related conditions such as delivery and breastfeeding are discussed. 
546 |a EN 
690 |a COVID-19 
690 |a SARS-CoV-2 
690 |a Pregnant women 
690 |a Vertical transmission 
690 |a Prevention 
690 |a Infectious and parasitic diseases 
690 |a RC109-216 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Journal of Infection and Public Health, Vol 14, Iss 7, Pp 863-875 (2021) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1876034121000976 
787 0 |n https://doaj.org/toc/1876-0341 
856 4 1 |u https://doaj.org/article/2edfa64d8c714fb0aa8a43ac2da9945c  |z Connect to this object online.