Reliable HPLC-UV method for therapeutic levetiracetam monitoring in serum and cerebrospinal fluid of patients with epilepsy

• Main Authors: Anna Wesołowska (Author), Elżbieta Szczygieł-Pilut (Author), Łukasz Hońdo (Author), Kinga Wojewodzic (Author), Sylwia Kozłowska (Author), Anna Zajączkowska-Dutkiewicz (Author), Daniel Pilut (Author), Michał Michalski (Author), Agnieszka Cios (Author)
• Format: Book
• Published: Polskie Towarzystwo Farmaceutyczne, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study was to develop and validate a rapid analytical method of high-performance liquid chromatography with UV (HPLC/UV) detection for the determination of levetiracetam (LEV) concentration in human serum and cerebrospinal fluid (CSF) samples. The newly developed method was used to measur...