Beneficial haemodynamic effect of indomethacin during endotoxin shock in anaesthetized pigsputative involvement of nitric oxide?

• Asıl Yazarlar: T. Mózes (Yazar), E. M. van Gelderen (Yazar), E. J. Mylecharane (Yazar), P. R. Saxena (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 1995-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Endotoxin shock was induced in 31 anaesthetized pigs by infusion of 5 μg/kg of Escbeicbia coli endotoxin (LPS) over 60 min into the superior mesenteric artery. Fifteen of these pigs died within 30 min of the start of LPS infusion whereas the remaining 16 survived the experimental period of 2 h. In a...