Alterations in B cell development, CDR-H3 repertoire and dsDNA-binding antibody production among C57BL/6 ΔD−iD mice congenic for the lupus susceptibility loci sle1, sle2 or sle3
Systemic lupus erythematosus (SLE) is an autoimmune disease that reflects a failure to block the production of self-reactive antibodies, especially those that bind double-stranded DNA (dsDNA). Backcrossing the lupus-prone NZM2410 genome onto C57BL/6 led to the identification of three genomic interva...
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Main Authors: | Mohamed Khass (Author), Robert L. Schelonka (Author), Cun Ren Liu (Author), Ada Elgavish (Author), Laurence Morel (Author), Peter D. Burrows (Author), Harry W. Schroeder (Author) |
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Format: | Book |
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Taylor & Francis Group,
2017-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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