AKR1C3 in carcinomas: from multifaceted roles to therapeutic strategies
Aldo-Keto Reductase Family 1 Member C3 (AKR1C3), also known as type 5 17β-hydroxysteroid dehydrogenase (17β-HSD5) or prostaglandin F (PGF) synthase, functions as a pivotal enzyme in androgen biosynthesis. It catalyzes the conversion of weak androgens, estrone (a weak estrogen), and PGD2 into potent...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2024-03-01T00:00:00Z.
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