TLR2 Elicits IL-17-Mediated RANKL Expression, IL-17, and OPG Production in Neutrophils from Arthritic Mice

We investigated the ability of neutrophils to express receptor activator of nuclear factor kappa-B ligand (RANKL), to secrete osteoprotegerin (OPG), and to produce IL-17. Arthritis was induced by intra-articular injection of zymosan, a ligand for Toll-like receptor 2 (TLR2). Frequencies of neutrophi...

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Bibliographic Details
Main Authors: Viktoriya Milanova (Author), Nina Ivanovska (Author), Petya Dimitrova (Author)
Format: Book
Published: Hindawi Limited, 2014-01-01T00:00:00Z.
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