Comparison of oral midazolam with a combination of oral midazolam and nitrous oxide-oxygen inhalation in the effectiveness of dental sedation for young children

<b>Aim: </b> To compare the effectiveness of 0.6 mg/kg oral midazolam sedation alone and a combination of 0.6 mg/kg oral midazolam plus nitrous oxide-oxygen inhalation sedation, in controlling the behavior of uncooperative children during dental treatment. <b> Study Design:</b&g...

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Bibliographic Details
Main Authors: Al-Zahrani A (Author), Wyne A (Author), Sheta S (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2009-03-01T00:00:00Z.
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Summary:<b>Aim: </b> To compare the effectiveness of 0.6 mg/kg oral midazolam sedation alone and a combination of 0.6 mg/kg oral midazolam plus nitrous oxide-oxygen inhalation sedation, in controlling the behavior of uncooperative children during dental treatment. <b> Study Design:</b> The study had a crossover design where the same patient received two different sedation regimens, that is, oral midazolam 0.6 mg/kg and oral midazolam 0.6 mg/kg with nitrous oxide-oxygen inhalation during two dental treatment visits. <b> Materials and Methods: </b> Thirty children (17 males and 13 females) were randomly selected for the study, with a mean age of 55.07 (&#x00B1; 9.29) months, ranging from 48 - 72 months.<b> </b> A scoring system suggested by Houpt et al. (1985) was utilized for assessment of the children&#x2032;s behavior. <b> Results</b> : There was no significant (p &gt; 0.05) difference in the overall behavior assessment between the two sedation regimens, that is, oral midazolam alone and oral midazolam plus nitrous oxide-oxygen. However, the combination of midazolam and nitrous oxide-oxygen showed significantly (p &lt; 0.05) superior results as compared to midazolam alone, in terms of controlling movement and crying during local anesthesia administration and restorative procedures. <b> Conclusion:</b> Compared to oral midazolam alone, a combination of oral midazolam and nitrous oxide inhalation sedation appears to provide more comfort to pediatric dental patients and operators during critical stages of dental treatment.
Item Description:0970-4388