Development of Solvent-Free Co-Ground Method to Produce Terbinafine Hydrochloride Cyclodextrin Binary Systems; Structural and In Vitro Characterizations

• Main Authors: Balázs Attila Kondoros (Author), Orsolya Jójárt-Laczkovich (Author), Ottó Berkesi (Author), Piroska Szabó-Révész (Author), Ildikó Csóka (Author), Rita Ambrus (Author), Zoltán Aigner (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Molecular complexation with cyclodextrins (CDs) has long been a known process for modifying the physicochemical properties of problematic active pharmaceutical ingredients with poor water solubility. In current times, the focus has been on the solvent-free co-grinding process, which is an industrial...