Influenza vaccine effectiveness among high-risk groups: A systematic literature review and meta-analysis of case-control and cohort studies
Vaccination represents the most effective intervention to prevent infection, hospitalization and mortality due to influenza. This meta-analysis quantifies data reporting influenza vaccine effectiveness (VE) on influenza visits and hospitalizations of case-control and cohort studies among high-risk g...
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Format: | Book |
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Taylor & Francis Group,
2018-03-01T00:00:00Z.
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001 | doaj_2f7ed32e5e4b415d9e7f83c93bb36f93 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Vincenzo Restivo |e author |
700 | 1 | 0 | |a Claudio Costantino |e author |
700 | 1 | 0 | |a Stefania Bono |e author |
700 | 1 | 0 | |a Marialuisa Maniglia |e author |
700 | 1 | 0 | |a Valentina Marchese |e author |
700 | 1 | 0 | |a Gianmarco Ventura |e author |
700 | 1 | 0 | |a Alessandra Casuccio |e author |
700 | 1 | 0 | |a Fabio Tramuto |e author |
700 | 1 | 0 | |a Francesco Vitale |e author |
245 | 0 | 0 | |a Influenza vaccine effectiveness among high-risk groups: A systematic literature review and meta-analysis of case-control and cohort studies |
260 | |b Taylor & Francis Group, |c 2018-03-01T00:00:00Z. | ||
500 | |a 2164-5515 | ||
500 | |a 2164-554X | ||
500 | |a 10.1080/21645515.2017.1321722 | ||
520 | |a Vaccination represents the most effective intervention to prevent infection, hospitalization and mortality due to influenza. This meta-analysis quantifies data reporting influenza vaccine effectiveness (VE) on influenza visits and hospitalizations of case-control and cohort studies among high-risk groups. A systematic literature review including original articles published between 2007 and 2016, using a protocol registered on Prospero with No. 42017054854, and a meta-analysis were conducted. For 3 high-risk groups (subjects with underlying health conditions, pregnant women and health care workers) only a qualitative evaluation was performed. The VE quantitative analysis demonstrated a clear significant overall effect of 39% (95%CI: 32-46%) for visits and 57% (95%CI: 30-74%) for hospitalization among children. Considering the elderly influenza VE had a clear effect of 25% (95%CI: 6-40%) for visits and 14% (95%CI: 7-21%; p<0.001) for hospitalization. This study showed the high VE of influenza vaccination among high-risk groups, representing a tool for public health decision-makers to develop evidence-based preventive interventions to avoid influenza outcomes. | ||
546 | |a EN | ||
690 | |a children | ||
690 | |a chronic disease | ||
690 | |a effectiveness | ||
690 | |a elderly subjects | ||
690 | |a health care worker | ||
690 | |a hospitalization | ||
690 | |a influenza | ||
690 | |a pregnancy | ||
690 | |a vaccine | ||
690 | |a visit | ||
690 | |a Immunologic diseases. Allergy | ||
690 | |a RC581-607 | ||
690 | |a Therapeutics. Pharmacology | ||
690 | |a RM1-950 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Human Vaccines & Immunotherapeutics, Vol 14, Iss 3, Pp 724-735 (2018) | |
787 | 0 | |n http://dx.doi.org/10.1080/21645515.2017.1321722 | |
787 | 0 | |n https://doaj.org/toc/2164-5515 | |
787 | 0 | |n https://doaj.org/toc/2164-554X | |
856 | 4 | 1 | |u https://doaj.org/article/2f7ed32e5e4b415d9e7f83c93bb36f93 |z Connect to this object online. |