Mandibular bone necrosis after use of paraformaldehyde-containing paste

Paraformaldehyde has been used in the past as a pulpotomy agent. However, it has a severe cytotoxic effect and may cause alveolar bone necrosis. Depulpin, a devitalizing agent containing 49% paraformaldehyde, is no longer used frequently due to its severe side effects. In the two cases described in...

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Bibliographic Details
Main Authors: Chi-hwan Lee (Author), Yoorina Choi (Author), Sujung Park (Author)
Format: Book
Published: Korean Academy of Conservative Dentistry, 2016-11-01T00:00:00Z.
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Summary:Paraformaldehyde has been used in the past as a pulpotomy agent. However, it has a severe cytotoxic effect and may cause alveolar bone necrosis. Depulpin, a devitalizing agent containing 49% paraformaldehyde, is no longer used frequently due to its severe side effects. In the two cases described in the present study, Depulpin was used as a devitalizing agent during root canal treatment. It caused a gradual loss of sensibility in adjacent teeth, gingival necrosis, and osteomyelitis. This case report demonstrates the serious side effects of using a paraformaldehyde-containing paste as a devitalizing agent for pulp, particularly mandibular bone necrosis.
Item Description:10.5395/rde.2016.41.4.332
2234-7658
2234-7666