Population pharmacokinetic analysis, renal safety, and dosing optimization of polymyxin B in lung transplant recipients with pneumonia: A prospective study

• Main Authors: Xiao-Jun Cai (Author), Yan Chen (Author), Xiao-Shan Zhang (Author), Yu-Zhen Wang (Author), Wen-Bo Zhou (Author), Chun-Hong Zhang (Author), Bo Wu (Author), Hui-Zhu Song (Author), Hang Yang (Author), Xu-Ben Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: This study aims to characterize the population pharmacokinetics of polymyxin B in lung transplant recipients and optimize its dosage regimens.Patients and methods: This prospective study involved carbapenem-resistant organisms-infected patients treated with polymyxin B. The population ph...