Benign Histiocyte-Rich Pseudotumor Developing Postchemotherapy and Mimicking Residual Disease

Histiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diff...

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Bibliographic Details
Main Authors: Amrit P. Singh (Author), Glenn P. Murray (Author), Soumya Pandey (Author)
Format: Book
Published: Hindawi Limited, 2020-01-01T00:00:00Z.
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Summary:Histiocyte-rich pseudotumors (HRPT) developing postchemoradiation therapy are a florid response to treatment and reparative change. Although these are benign processes, clinically and radiologically, these may mimic recurrent/relapsed disease. We describe a case of an adult male with history of diffuse large B-cell lymphoma (DLBCL), status postchemoradiation therapy, who developed HRPT at the site of original involvement, mimicking relapse of disease on positron emission tomography/computed tomography (PET/CT) imaging. This is one of the few reported cases of posttreatment HRPT. This entity is important to point out the limitations of PET/CT imaging in patients with lymphomas and metastatic disease and stresses the importance of an excisional biopsy for determining relapse and the need for further treatment.
Item Description:2090-6781
2090-679X
10.1155/2020/4674103