Safety Testing of an Antisense Oligonucleotide Intended for Pediatric Indications in the Juvenile Göttingen Minipig, including an Evaluation of the Ontogeny of Key Nucleases
The adult Göttingen Minipig is an acknowledged model for safety assessment of antisense oligonucleotide (ASO) drugs developed for adult indications. To assess whether the juvenile Göttingen Minipig is also a suitable nonclinical model for pediatric safety assessment of ASOs, we performed an 8-week r...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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